Error when burning bootloader

Hi, I am new to esp32 development, and as it always happens as newbie, I got the following error:

[info] Burning bootloader...
[info] Burning bin
[info] esptool.py v2.0
[info] Traceback (most recent call last):
[info]   File "C:\Users\xx\zerynth2\dist\r2.6.3\sys\esptool\esp32\esptool.py", line 2405, in 
[info]     _main()
[info]   File "C:\Users\xx\zerynth2\dist\r2.6.3\sys\esptool\esp32\esptool.py", line 2398, in _main
[info]     main()
[info]   File "C:\Users\xx\zerynth2\dist\r2.6.3\sys\esptool\esp32\esptool.py", line 2127, in main
[info]     esp = chip_class(args.port, initial_baud)
[info]   File "C:\Users\xx\zerynth2\dist\r2.6.3\sys\esptool\esp32\esptool.py", line 175, in __init__
[info]     self._port = serial.serial_for_url(port)
[info]   File "C:\Users\xx\zerynth2\sys\python\lib\site-packages\serial\__init__.py", line 78, in serial_for_url
[info]     instance.open()
[info]   File "C:\Users\xx\zerynth2\sys\python\lib\site-packages\serial\serialwin32.py", line 66, in open
[info]     raise SerialException("could not open port %r: %r" % (self.portstr, ctypes.WinError()))
[info] serial.serialutil.SerialException: could not open port 'COM5': FileNotFoundError(2, 'Das System kann die angegebene Datei nicht finden.', None, 2)
[error] Can't burn bootloader! --> esptool.py v2.0
Traceback (most recent call last):
  File "C:\Users\xx\zerynth2\dist\r2.6.3\sys\esptool\esp32\esptool.py", line 2405, in 
    _main()
  File "C:\Users\xx\zerynth2\dist\r2.6.3\sys\esptool\esp32\esptool.py", line 2398, in _main
    main()
  File "C:\Users\xx\zerynth2\dist\r2.6.3\sys\esptool\esp32\esptool.py", line 2127, in main
    esp = chip_class(args.port, initial_baud)
  File "C:\Users\xx\zerynth2\dist\r2.6.3\sys\esptool\esp32\esptool.py", line 175, in __init__
    self._port = serial.serial_for_url(port)
  File "C:\Users\xx\zerynth2\sys\python\lib\site-packages\serial\__init__.py", line 78, in serial_for_url
    instance.open()
  File "C:\Users\xx\zerynth2\sys\python\lib\site-packages\serial\serialwin32.py", line 66, in open
    raise SerialException("could not open port %r: %r" % (self.portstr, ctypes.WinError()))
serial.serialutil.SerialException: could not open port 'COM5': FileNotFoundError(2, 'Das System kann die angegebene Datei nicht finden.', None, 2)
[info] Starting device registration
[info] Burning bootloader...
[info] Burning bin
[info] esptool.py v2.0
[info] Traceback (most recent call last):
[info]   File "C:\Users\xx\zerynth2\dist\r2.6.3\sys\esptool\esp32\esptool.py", line 2405, in 
[info]     _main()
[info]   File "C:\Users\xx\zerynth2\dist\r2.6.3\sys\esptool\esp32\esptool.py", line 2398, in _main
[info]     main()
[info]   File "C:\Users\xx\zerynth2\dist\r2.6.3\sys\esptool\esp32\esptool.py", line 2127, in main
[info]     esp = chip_class(args.port, initial_baud)
[info]   File "C:\Users\xx\zerynth2\dist\r2.6.3\sys\esptool\esp32\esptool.py", line 175, in __init__
[info]     self._port = serial.serial_for_url(port)
[info]   File "C:\Users\xx\zerynth2\sys\python\lib\site-packages\serial\__init__.py", line 78, in serial_for_url
[info]     instance.open()
[info]   File "C:\Users\xx\zerynth2\sys\python\lib\site-packages\serial\serialwin32.py", line 66, in open
[info]     raise SerialException("could not open port %r: %r" % (self.portstr, ctypes.WinError()))
[info] serial.serialutil.SerialException: could not open port 'COM5': FileNotFoundError(2, 'Das System kann die angegebene Datei nicht finden.', None, 2)
[error] Can't burn bootloader! --> esptool.py v2.0
Traceback (most recent call last):
  File "C:\Users\xx\zerynth2\dist\r2.6.3\sys\esptool\esp32\esptool.py", line 2405, in 
    _main()
  File "C:\Users\xx\zerynth2\dist\r2.6.3\sys\esptool\esp32\esptool.py", line 2398, in _main
    main()
  File "C:\Users\xx\zerynth2\dist\r2.6.3\sys\esptool\esp32\esptool.py", line 2127, in main
    esp = chip_class(args.port, initial_baud)
  File "C:\Users\xx\zerynth2\dist\r2.6.3\sys\esptool\esp32\esptool.py", line 175, in __init__
    self._port = serial.serial_for_url(port)
  File "C:\Users\xx\zerynth2\sys\python\lib\site-packages\serial\__init__.py", line 78, in serial_for_url
    instance.open()
  File "C:\Users\xx\zerynth2\sys\python\lib\site-packages\serial\serialwin32.py", line 66, in open
    raise SerialException("could not open port %r: %r" % (self.portstr, ctypes.WinError()))
serial.serialutil.SerialException: could not open port 'COM5': FileNotFoundError(2, 'Das System kann die angegebene Datei nicht finden.', None, 2)

This error occures, when I try to register my board with zerynth studio.
If I understand the error message right, it tries to run the bootloader on the esp32 with the help of the esptool.py and recieves some sort of error or access denied status.
I am using the ESP32 DevKitC board and I am on win10.

hi @Dominik_Lovetinsky
This might occur due to missing hardware drivers, are you sure you have the appropriate hardware drivers for the board?
After downloading the drivers, try to open a serial terminal session with the board in putty for instance.
also, Make sure there isn’t any other application that currently opens this device for communication.